Question 1 — ₹1,000
On September 28, 1928, Scottish medical researcher Alexander Fleming made a groundbreaking discovery that revolutionized modern medicine. Which first broadly effective antibiotic did he discover?
A) Streptomycin
B) Penicillin
C) Tetracycline
D) Amoxicillin
Correct Answer: B) Penicillin
Explanation: Alexander Fleming discovered penicillin at St. Mary's Hospital in London on September 28, 1928, after noticing that a mould called Penicillium notatum had contaminated a culture plate of staphylococci and inhibited bacterial growth.
Question 2 — ₹2,000
In September 2020, which prestigious American research institution reported that the global confirmed death toll from the COVID-19 pandemic had officially surpassed the grim milestone of 1 million?
A) Stanford University
B) Johns Hopkins University
C) Harvard University
D) Mayo Clinic
Correct Answer: B) Johns Hopkins University
Explanation: The Coronavirus Resource Center at Johns Hopkins University, which served as a primary global tracker during the pandemic, confirmed on September 28, 2020, that worldwide COVID-19 fatalities had crossed 1 million.
Question 3 — ₹5,000
In 1781, American continental forces and allied French troops laid siege to British forces in which historic Virginia settlement, leading to the decisive battle of the American Revolutionary War?
A) Jamestown
B) Richmond
C) Yorktown
D) Williamsburg
Correct Answer: C) Yorktown
Explanation: On September 28, 1781, General George Washington's allied American and French forces commenced the Siege of Yorktown, Virginia, culminating in the surrender of British General Lord Cornwallis and effectively sealing American victory.
Question 4 — ₹10,000
In 1995, an interim peace accord (Oslo II) aimed at expanding Palestinian self-rule in the West Bank was signed at the White House by Israeli Prime Minister Yitzhak Rabin and which leader of the Palestine Liberation Organization (PLO)?
A) Mahmoud Abbas
B) Yasser Arafat
C) Ismail Haniyeh
D) Saeb Erekat
Correct Answer: B) Yasser Arafat
Explanation: On September 28, 1995, PLO Chairman Yasser Arafat and Israeli PM Yitzhak Rabin signed the Israeli-Palestinian Interim Agreement on the West Bank and Gaza Strip (Oslo II), establishing phased redeployment of Israeli forces.
Question 5 — ₹20,000
Which deadly storm made landfall in southwestern Florida on September 28, 2022, as a powerful Category 4 storm, resulting in over 100 fatalities and massive infrastructure damage?
A) Hurricane Katrina
B) Hurricane Ian
C) Hurricane Ida
D) Hurricane Michael
Correct Answer: B) Hurricane Ian
Explanation: Hurricane Ian made landfall on September 28, 2022, near Cayo Costa in southwestern Florida with sustained winds of roughly 150 mph, making it one of the costliest natural disasters in US history.
Question 6 — ₹40,000
In 1941, legendary Boston Red Sox player Ted Williams achieved a historic feat that has not been matched in Major League Baseball since. What season-ending accomplishment did he achieve?
A) 60 Home Runs
B) Batting over .400 (.406)
C) 2,000 Base Hits
D) 150 Runs Batted In
Correct Answer: B) Batting over .400 (.406)
Explanation: On September 28, 1941, Ted Williams finished the season with a .406 batting average, becoming the last player in Major League Baseball history to hit over .400 in a single regular season.
Question 7 — ₹80,000
In September 2016, which powerful tropical cyclone formed near the Windward Islands, eventually causing over 1,000 deaths across the Caribbean—most severely in southwestern Haiti—and the southeastern United States?
A) Hurricane Dorian
B) Hurricane Matthew
C) Hurricane Maria
D) Hurricane Irma
Correct Answer: B) Hurricane Matthew
Explanation: Hurricane Matthew formed in late September 2016 and intensified into a Category 5 hurricane, ravaging Haiti's Tiburon Peninsula and parts of Cuba, the Bahamas, and the US Atlantic coast.
Question 8 — ₹1,60,000
In 1924, aviators flying Douglas World Cruisers landed in Seattle to complete the world's first aerial circumnavigation. How long did this historic U.S. Army Air Service expedition take?
A) 80 days
B) 120 days
C) 175 days
D) 240 days
Correct Answer: C) 175 days
Explanation: Four open-cockpit biplanes departed Seattle in April 1924, and after traversing 27,550 miles across 175 days, two of the original aircraft (along with a replacement) successfully returned to Seattle on September 28, 1924.
Question 9 — ₹3,20,000
In September 1962, a US federal court held Mississippi Governor Ross Barnett in civil contempt for physically attempting to block which African American student from enrolling at the University of Mississippi?
A) James Meredith
B) Medgar Evers
C) Ruby Bridges
D) John Lewis
Correct Answer: A) James Meredith
Explanation: Military veteran James Meredith fought a legal battle to integrate the University of Mississippi (Ole Miss). On September 28, 1962, Governor Ross Barnett was cited for contempt of court for defying federal integration orders.
Question 10 — ₹6,40,000
In September 2000, capping a 12-year legal and political battle, the US Food and Drug Administration (FDA) approved which synthetic pharmaceutical compound, widely known as the mifepristone pill (RU-486)?
A) RU-486
B) AZT-100
C) VX-765
D) MK-801
Correct Answer: A) RU-486
Explanation: Developed in France by Roussel-Uclaf, mifepristone was designated RU-486 during clinical trials. On September 28, 2000, the US FDA formally approved its use as an early medical pregnancy termination drug.
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